唐氏综合症是什么（唐氏综合征是什么时候形成的）

??姘?缁煎??寰????涔?

??璋?????姘?缁煎??寰??跺???????蹭????崇??锛?涔?琚?О涓烘??1-涓?浣?缁煎??寰?????澶╂????锛?涓昏????辨???蹭?????寮?甯革??冲?浜?涓???1?锋???蹭???瀵艰?寸???剧????

?????╄?纭???????蹭???锛?60%?ｅ?垮?ㄨ?????╂???冲き??娴?浜э?瀛?娲昏???????剧???鸿?借?藉?????规??㈠?锛????垮???查??纰???澶????稿舰??

??姘?缁煎??寰???琛ㄧ??/strong>

?ｄ???姘?缁煎??寰??????夸???濡?涓?杩?浜????惰〃?帮?

1?????挎?ｄ???姘?缁煎??寰???璇?锛?瀹硅???浣???浼?????????锛?濡??艰?灏?锛??煎?渚т?????韬????????澶村?村?浜?姝ｅ父绛???

2????姘?缁煎??寰??????挎?????＄??涔??????甯告?哄??涔?姣?骞冲父浜轰?锛???涓????借?浼??虹?板???诲?伴?撅?浠ュ??琛?涓哄???у???插??灞?寤惰???

3????姘?缁煎??寰??????块?垮ぇ浠ュ?????戒???复??涓?瀛?涓??茬?????锛?涓?杩?濡???濂虫?ч?垮ぇ???ユ??缁???璇?锛???涔????????界???茬????

4??浼存???朵?蹇???绛????锛???涓??借???????????姣?涓???汉??瑕?楂?锛?甯稿父??0宀?宸﹀?冲氨?虹?拌??骞寸?村????

??姘?缁煎??寰???涔?寮?璧风??

??姘?缁煎????????涔?寮?璧风??锛???????????????????哄?惰?璧枫??

1??????????

??姘?缁煎??寰???????涓?姣?浜叉??瀛?骞撮????稿?筹?绯?1?锋???蹭???寮?甯革???涓?浣?锛???浣???宓???3绉?绫诲??锛?姣?榫?楂?锛??靛???????????涓???绂荤????瑕???????

2???????哄?

涓?浣?????捣???舵???娈?缁??????板??瑁???21?锋???蹭???涓???绂伙??跺?????哄?剁郴??浜蹭唬(澶??颁负姣???????娈?缁????ㄥ???板??瑁??讹????蹭?涓???绂绘???达?瀛?濡?骞撮?瓒?澶э???姘?缁煎??寰??????????芥?ц?澶?琛?)锛??ㄥ?姝ｅ父浜???浣??舵?灞＄??21-涓?浣??跨??瀹舵????绌朵腑???帮??舵???娈?缁???瀛??ㄧ??宓???21-涓?浣?缁???绯诲??姣?婧?21?锋???蹭?????浜蹭?浣?涔???????21-涓?浣???????锛???浣??????辩?舵?涔?涓?涓?1?锋???蹭?骞宠　??浣??哄甫????浼????ワ??ゆ?????蹭???浣?澶?锛???浜插??ㄨ?娣?宸寸????稿??澶ч?芥?甯革?浜х????姘?缁煎??寰?琛ㄥ???瑰???21?锋???蹭????抽???ㄤ???1q22.1锝?q22.2锛?涓??????涓??哄甫??21?ㄥ??涓?浣???涓?????own缁煎??寰???

??姘?缁煎??寰???涔?妫???/strong>

?ラ??浜???姘?缁煎???????涔?锛??ｄ???涔??绘??ヨ?涓??剧?????涓?????浠????ㄥ??姘?缁煎????浜у??绛??ワ?绠?绉板??绛???

??姘?缁煎????浜у??绛??ユ???涔?????跺???姘?缁煎????涔?绉?1涓?浣?缁煎??寰?锛???姘?缁煎????绠??????蹭???寮??剧????涓?????姘?缁煎??????互?ㄤ骇??琚?????烘?ワ????规?????垫?ュ?冲?瀛?濡????︾户缁??濞?锛??跺???姘?缁煎????浜у??绛??ョ????????杩???楠?瀛?濡???琛?娑诧?缁????朵?涓村?淇℃????ョ患???ゆ?????挎?ｆ????姘??????遍?╃?搴︼?濡?????绛?妫??ョ????剧ず???挎?ｆ????姘?缁煎???????遍?╂?ф?杈?楂?锛?灏卞?杩?涓?姝ヨ?琛?纭???х??妫??ワ?灏辨???琛?缇???绌垮?烘??ユ??缁?姣?妫??ワ???涓?????姘?缁煎????浼?璁╄???垮き??锛????堕『?╃??浜у?烘?ワ?濠村?夸?浼????垮???查??纰???澶????稿舰??

浠?涔?????姘?缁煎????锛?

??姘?缁煎??寰???1-涓?浣?缁煎??寰?锛???绉板??澶╂??????Down缁煎??寰?锛????辨???蹭?寮?甯革?澶?浜?涓???1?锋???蹭?锛???瀵艰?寸???剧????60%?ｅ?垮?ㄨ?????╂???虫?浜э?瀛?娲昏???????剧???鸿?借?藉?????规??㈠??????垮???查??纰???澶????稿舰????姘?缁煎??寰???????涓?姣?浜叉??瀛?骞撮????稿?筹?绯?1?锋???蹭???寮?甯革???涓?浣?????浣???宓???涓?绉?绫诲????楂?榫?瀛?濡????靛???????????涓???绂荤????瑕???????
涓村?琛ㄧ??br />1.?ｅ?垮?锋???剧???规??㈠?浣?寰?锛?濡??艰?瀹斤?榧绘?逛?骞筹??艰?灏?锛??煎?渚т???锛??????﹁????澶??冲?锛?????锛?甯镐几?哄?ｅ?锛?娴?娑?澶???韬??????锛?澶村?村?浜?姝ｅ父锛?澶村??????寰???????ㄥ钩????澶淬??棰????????ゅ??俱??楠ㄩ?甯歌?藉??浜?骞撮?锛??虹??寤惰?涓?甯搁??浣???澶村??缁?杞???杈?灏?????????????锛?椤舵??涓?嚎????绗?????ㄣ?????㈢????变??у甫?惧?锛??宠?????搴﹀集?诧?????绮????灏???涓???楠ㄥ???蹭???娇灏???????寮??诧???楠ㄧ???????涓????瑰??杩?绔?Щ浣?锛?甯歌???璐???绾广??????瓒筹???瓒剧???ㄧ害???版?ｅ?垮??寮?褰㈢??汗??
2.甯稿???板???″?????诲?伴?撅??舵?鸿?戒?涓?琛ㄧ?伴??骞撮?澧??胯????娓????撅??哄??25锝?50锛??ㄤ????插???у???查?藉欢杩???
3.?锋?у??姘?濠村?块?垮ぇ?抽???ユ??锛?涔?涓?浼??????茶?藉??????濂虫?у??姘?濠村?块?垮ぇ??????缁?锛?骞朵??????界???层??
4.?ｅ?垮父浼存????澶╂?у?????绛??朵??稿舰锛??????????戒?涓?锛????ｅ??绉?????锛??借???????????姣?涓????楂?10锝?30????濡?瀛?娲昏?虫??浜烘??锛???甯稿??0宀?浠ュ???冲?虹?拌??骞存?х?村?????躲??
妫???br />1.瀵瑰??ㄨ?缁??????蹭??稿??????
缁?????浼?瀛︾??绌跺???帮???1?锋???蹭??胯??21q22?哄甫涓轰?浣??讹?璇ヤ釜浣??锋??瀹??ㄧ被浼煎??姘?缁煎??寰???涓村?琛ㄧ?帮??稿??锛?璇ュ?哄甫涓洪??涓?浣???涓??????姝ゅ?稿?????躲???辨??ㄨ?锛?21q22?哄???芥????姘?缁煎??寰????哄???抽???哄甫锛???绉颁负??姘?缁煎??寰??恒???????蹭??稿???????????姘?缁煎??寰??ｅ?垮??涓轰???锛?
锛?1锛??????????ㄩ?ㄧ??渚???95%???ｅ?夸?缁??????蹭?涓?7?★???涓?涓??澶???21?锋???蹭?锛??稿??涓?7锛?XX锛???XY锛?锛?+21??
锛?2锛???浣?????2.5%锝?5%锛??ｅ?跨?????蹭??绘?颁负46?★?澶?涓虹?浼?????浣?锛??????????ㄨ?绔???涓?绮????蹭???涓?绉??镐???浣?锛?澶?涓?/G??浣?锛?D缁?涓?互14?锋???蹭?涓轰富锛??虫?稿??涓?6锛?XX锛???XY锛?锛?-14锛?+t锛?14q21q锛?锛?灏??颁负15?锋???蹭???浣?锛?杩?绉???浣????ｅ?跨害???颁负??浼??э??充翰浠ｄ腑??骞宠　??浣????蹭??哄甫?????︿?绉?涓?/G??浣?锛?杈?灏?瑙?锛????变?G缁?涓?涓?1?锋???蹭???????涓?绮?????锛?褰㈡??绛??????蹭?t锛?21q21q锛?锛???1涓?1?锋??浣???涓?2?锋???蹭?涓???
锛?3锛?宓???浣???????????2%锝?4%锛??ｅ?夸?????2绉?????2绉?浠ヤ?缁??????浠?绉?涓哄?瑙?锛?锛?涓????甯革??︿???负21-涓?浣?缁???锛?涓村?琛ㄧ?扮??涓ラ??绋?搴︿?姝ｅ父缁????????惧??姣????筹???互浠??ヨ?姝ｅ父?板?稿??琛ㄥ??锛?21-涓?浣?缁??????渚?瓒?楂?锛??哄???藉?????稿舰??绋?搴﹁?????
2.缇?姘寸??????蹭?妫???br />缇?姘寸??????蹭?妫??ユ????姘?缁煎??寰?浜у??璇?????涓?绉??????规?锛???姘?绛??ョ???涓衡??楂??扁????瀛?濡???瑕?纭?????挎???︿负??姘?缁煎??寰??ｅ?裤??????浜у??璇?????甯哥?ㄧ?????????????绌垮?烘??????冲??瓒?寮?瀵间?锛?灏?????杩?瀛?濡??归?ㄥ?哄?ョ?姘翠腑锛??藉??缇?姘达?瀵硅???跨???杩?琛????蹭?????????瀹?瀛?16锝?20?ㄧ??瀛?濡????ょ?????绌垮?烘???锛?杩?琛?浜у??璇????????????缁?姣?娲绘??????胯??????绌垮?恒?????块??妫??ョ???甯歌??稿??涓?澶??ㄨ?缁??????蹭??稿???稿????
3.?у????浣???浜?br />浠?1?锋???蹭????稿??ㄤ?搴???浣??㈤??锛?涓?澶??ㄨ?涓???娣?宸寸?????缇?姘寸???杩?琛???浜わ???姘?缁煎??寰??ｈ????缁???涓???????涓?1?锋???蹭????у??淇″?枫???ラ???╁??姘?缁煎??寰??稿??虹???瑰?搴???浣?涓烘?㈤??锛?杩?琛?FISH??浜ゅ????锛???互瀵?1?锋???蹭???寮?甯搁?ㄤ?杩?琛?绮剧‘瀹?浣?锛???楂?妫?娴?21?锋???蹭??扮????缁???寮?甯哥??绮剧‘?с??
4.浜у??绛??ヨ?娓???蹇???br />???ㄦ?瀹?瀛?濡?琛?娓?缁?姣???淇??ц?烘?绱?锛?HCG锛????茶?????斤?AFP锛???娓哥???涓???锛?FE3锛?杩?琛???姘?缁煎??寰?绛??ョ???㈢储宸叉??澶?骞达?杩????绉???瀛?涓???????锛?13?ㄤ互??锛???
?规???3椤癸?涔????瀹?HCG??AFP涓ら」锛?琛?娓?瀛︽????浠ュ??瀛?濡?骞撮???浣????ユ?ㄧ???????姘?缁煎??寰??ｅ?跨??椋??╃??锛??规????╃????楂?浣???杩?涓?姝ヨ?琛?纭??妫??ャ??
5.甯歌???X绾跨????瓒?澹般??蹇??靛?俱?????靛?剧?妫???br />?ㄥ???ｅ?垮?????板??澶╂?у?????锛?楠ㄩ??藉??锛????靛?惧?甯哥??瑰????
璇???br />???蹭??稿????????FISH?????璇ョ?????规??㈠????????圭?瑰???鸿?戒?涓??界?惰?戒负涓村?璇?????渚???瑕?绾跨储锛?浣????????寤虹?蹇?椤绘??璧?浜????蹭??稿??????锛???姝ゆ???蹭??稿????????FISH????????姘?缁煎??寰???涓昏?瀹?楠?瀹ゆ??ユ??????杩?涓ら」妫??ヨ?瀵瑰??姘?缁煎??寰?宓???????棰???浼拌???绉?????涔?锛??变?宓????稿舰?ｅ?跨??琛ㄥ??宸?????锛????姝ｅ父???ヨ?姝ｅ父?板?稿????涓村?琛ㄧ?帮?浠?浠???棰???涓昏????充??ｅ?夸?缁???涓??甯哥????????????惧??姣???????姝や?瑙ｅ??????ｅ?夸?缁???涓??甯告?稿??缁???涓?21-涓?浣??稿??缁?????姣?渚?锛???互?规???跺?蜂????垫??瀵兼?ｅ?跨??瀹跺涵??绀句?瀵瑰?惰?琛????层??
娌荤??
?变??ｅ?垮??????浣?涓?锛?瀹?娉ㄦ??棰??叉??????濡?浼存????澶╂?у????????????????朵??稿舰锛?????????????不??
棰???
濠村辜?挎?舵??甯稿??澶??ｅ?煎?搁??????锛?浼存????蹇???甯稿??姝ゆ?╂??姝讳骸????寮?????骞撮?澧??块??娓??瑰??锛??????垮???茶?搴︿?姝ｅ父?垮樊璺???娓???澶с??15宀??跺凡??姝㈤?块?锛?韬???????哄??浣?锛?宓?????????揪50%浠ヤ???濠村?挎?舵??琛ㄧ?颁负??涔?瀛╁???锛??跨??舵????缁??琛ㄧ?版??蹇??瀵逛汉浜插??锛?浣?????璋??ц?藉??宸??娉㈠?ㄨ?澶э????剁?稿??烘?у??璋?????瑕????ㄧ患?????斤??????荤????绀句????★?瀵规?ｈ??浠ヨ?琛??挎????蹇??????插??璁??锛?瀵瑰急?哄?胯?琛?棰?澶????蹭互浣垮?惰?借?娓″?版????瀛︽?′?瀛︼?璁??寮辨?哄?挎???′?瀹???宸ヤ????姐????蹇??版???插??璁??锛??ㄧ???や?锛???娲诲???????锛????冲????杈?绠?????绀句?宸ヤ???????跺????瀹堕?垮??瀛︽?″?甯??╁?瀛?????琛?涓洪???锛?绀句?搴?瀵规??惧?跨???舵?缁?浜???涔?涓?????????
棰???br />????灏???????娌荤???规?????濂芥??娈垫???ㄥ?濡?濡???浜у??缁?姝㈠?濞???瀛?濡?浜у??棰??插??瀹瑰?涓?锛?
1.??浼??ㄨ?
瀛?濡?骞撮???澶э?椋??╃????楂???????????姘?缁煎??寰???????椋??╃??涓?%????浣????ｅ?跨????浜插?杩?琛??稿??????锛?浠ヤ究???板钩琛℃??浣??哄甫??锛?濡?姣??逛负D/G??浣?锛???姣?涓????芥??10%??椋??╃??锛?濡??舵?逛负D/G??浣?锛???椋??╃??涓?%??缁?澶у???/G??浣???渚???涓烘?ｅ??锛??舵?浜叉?稿??澶у?姝ｅ父锛?浣?浜︽??????1/21??浣??哄甫??锛??朵?涓?浠?00%缃规?ｆ??????
2.浜у??璇???br />???叉???姘?缁煎??寰??ｅ?垮?虹???????????姐??宸叉??璇ョ?????插?茬??澶????娆＄???叉?跺?浣?浜у??璇?????虫???蹭??稿??????锛????峰?????涓???缇?????绌垮?轰?缇?姘寸?????瀛?涓???????缁?姣?缁?????瀛?涓?????甯﹁?娣?宸寸???绛???????浜у??绛??ヨ?娓???蹇???CG??AFP娴?瀹???涓?瀹?涓村???涔?锛???涓哄??藉???灏?缇???绌垮?鸿?琛?浜у??璇??????茬???э???绀洪??卞?濡?缇ょ??瀛????浣胯?浜?瀛?濡?寰?浠ヤ?杩?涓?姝ョ??浜у??妫??ュ???ㄨ?锛???澶ч??搴﹀?伴?叉???姘?缁煎??寰??ｅ?跨???虹????